Foundayo ▼
orforglipron - once-daily weight loss tablet
A tablet, not an injection
A once-daily tablet you can take at any time of day, with or without food.
Licensed by the MHRA for weight management in adults.
One tablet a day, at any time - no fasting window, no food or water restrictions
No needles and no fridge
Taken alongside a reduced-calorie diet and increased physical activity
12.4% average weight loss over 72 weeks at the highest dose in a clinical trial*
Foundayo is a prescription-only medicine. One of our clinicians will decide whether it is suitable for you. If it isn’t, you won’t be charged.
*ATTAIN-1, a 72-week trial in 3,127 adults with obesity or overweight. Highest dose, alongside a reduced-calorie diet and increased physical activity. The placebo group lost 0.9%. Individual results vary.
- GPhC Registered1088488
- UK LicensedMHRA Approved
GPhC RegisteredPharmacy: 1088488
UK Clinician-Led CareExpert support
Free DeliveryWithin 48 hours
100% DiscreetPlain packaging
At a glance
A quick summary of what makes Foundayo different - from how you take it to what you can expect.
12.4%
average weight loss
Over 72 weeks on the highest dose in the ATTAIN-1 trial, alongside a reduced-calorie diet and increased physical activity.
Once daily, any time
One tablet a day. With food or without. No fasting window and no restriction on what you drink.
No needles
A film-coated tablet you swallow whole. Nothing to inject and nothing to learn.
No fridge needed
Stored at room temperature in its original pack, so there are no cold-chain restrictions on where or when we can deliver.
What is Foundayo?
Foundayo is a once-daily tablet containing orforglipron, made by Eli Lilly. The MHRA authorised it on 10 August 2026, making the UK the first country in Europe to license it.
Orforglipron is a GLP-1 receptor agonist. It activates the same receptor as medicines like Wegovy, acting on the parts of the brain that regulate appetite. The effect is that you feel hungry less often, feel full sooner, and find it easier to eat less.
What makes it different?
What makes it different is its chemistry. Orforglipron is a small molecule rather than a peptide, which means it survives digestion without needing to be injected or taken on an empty stomach.
That is why it can be taken at any time of day, with or without food.
- Active ingredient
- Orforglipron
- Medication class
- GLP-1 agonist
- Administration
- Once-daily tablet
- Available doses
- 0.8mg - 17.2mg
- Average weight loss
- 12.4%*
- Licensed in UK
- Yes (MHRA approved)
Foundayo is a prescription-only medicine. One of our clinicians will decide whether it is suitable for you. If it isn’t, you won’t be charged.
Foundayo is manufactured by Eli Lilly and Company and is authorised in the UK for weight management by the Medicines and Healthcare products Regulatory Agency (MHRA). It is under additional monitoring — the black triangle symbol on this page reflects that.
Who Foundayo is for?
Foundayo is licensed for adults with a BMI of 30 or above, or a BMI between 27 and 30 alongside at least one weight-related health condition such as prediabetes, type 2 diabetes, high blood pressure, raised cholesterol, obstructive sleep apnoea or cardiovascular disease.
It is prescribed alongside a reduced-calorie diet and increased physical activity. Meeting the BMI criteria does not automatically mean it is right for you — one of our clinicians reviews your full medical history first.
Foundayo may suit you if
You want the benefits of a GLP-1 medicine without injecting- A daily tablet suits you better than remembering a weekly injection
- You travel often, or don’t have reliable fridge space
- You live somewhere our cold-chain deliveries can’t reliably reach
Foundayo is not suitable if you
Are pregnant, planning a pregnancy, or breast-feeding- Are allergic to orforglipron or any of the ingredients
- Have severe liver problems
- Are under 18
Tell your clinician if you have ever had pancreatitis, have severe problems with food leaving your stomach, have kidney, liver or gallbladder problems, have eye problems caused by diabetes, take insulin or a sulfonylurea, take medicine for high blood pressure, have severe heart failure, or are due to have surgery under general anaesthetic.
Switching from an injection?
If injections have never appealed, or the needle is the thing that has stopped you starting, Foundayo may be worth discussing with your clinician.
Switching is a clinical decision. Foundayo produces less weight loss on average than the injections, so if you are doing well on one and having no problems with it, we would usually suggest staying on it.
How well does Foundayo work?
In ATTAIN-1, a 72-week trial involving 3,127 adults, people taking the highest dose of Foundayo lost an average of 12.4% of their body weight, compared with 0.9% for those on placebo.
77.1%
lost 5%+
59.6%
lost 10%+
39.6%
lost 15%+
20.1%
lost 20%+
How it compares — and where it doesn’t
We want to be straight with you. Foundayo produces less weight loss on average than the injectable treatments. Its advantage isn’t maximum results — it’s that it’s a tablet you can take anywhere, at any time, without a needle or a fridge. For a lot of people, that is the difference between starting treatment and not starting at all, or between staying on it and giving up.
Foundayo
- Format
- Tablet
- How often
- Daily
- Fasting needed
- No
- Average weight loss
- 12.4%
- Storage
- Room temp
- Active ingredient
- Orforglipron
Wegovy tablet
- Format
- Tablet
- How often
- Daily
- Fasting needed
- Yes
- Average weight loss
- 14-17%
- Storage
- Room temp
- Active ingredient
- Semaglutide
Wegovy pen
- Format
- Injection
- How often
- Weekly
- Fasting needed
- No
- Average weight loss
- 15.3%
- Storage
- Fridge
- Active ingredient
- Semaglutide
Mounjaro
- Format
- Injection
- How often
- Weekly
- Fasting needed
- No
- Average weight loss
- 22.5%†
- Storage
- Fridge
- Active ingredient
- Tirzepatide
These figures come from separate clinical trials with different patients and different designs. They are not a head-to-head comparison and should be read as a general guide rather than a ranking. Individual results vary.
The 12.4% figure is the average change from baseline for everyone randomised to the highest dose, as reported in the UK Summary of Product Characteristics. Some sources quote 11.2%, which is a different statistical analysis of the same trial.
How to take Foundayo
Treatment starts at a low dose and increases slowly. You stay on each dose for at least 30 days before moving up, and only if you’re tolerating it well. Not everyone needs to reach the top dose — your clinician will help you find the lowest dose that works for you.
- 10.8mg30 days
- 22.5mg30 days
- 35.5mg30 days
- 49mg30 days
- 514.5mg30 days
- 617.2mgMaximum dose
One tablet a day
Never take two in one day to make up for a missed dose.
Any time that suits you
With food or without, and no restriction on what you drink.
Swallow it whole
Do not break, crush or chew the tablet.
If you miss a dose, take it as soon as you remember, then carry on as normal. Pick a time of day you’ll remember — with breakfast, at lunch, or before bed. It makes no clinical difference, so choose whatever fits your routine.
Foundayo
A tablet, not an injection
A once-daily tablet you can take at any time of day, with or without food. No needles, no fridge, no fasting window.
No needles, no fridge
A film-coated tablet you swallow whole. Stored at room temperature in its original pack — nothing to inject, nothing to keep cold.
Fits your routine
One tablet a day, at any time — with breakfast, at lunch, or before bed. No fasting window and no restriction on what you drink.
Honest about the trade-off
Foundayo produces less weight loss on average than the injections. Its advantage is that it fits into your life without a needle.
Possible Side Effects
Most side effects are temporary.
They typically improve as your body adjusts to the medication
and are most noticeable when starting or increasing doses.
Delivered across the UK
Foundayo is stored at room temperature. Unlike our injectable treatments, it doesn’t need cold-chain packaging or a temperature-controlled delivery window.
That means we can send it across the UK, including Northern Ireland and the Scottish Highlands, without the postcode restrictions and dispatch-day limits that apply to our injectable treatments.
It arrives in plain, discreet packaging with nothing on the outside to say what’s inside.
Keep your tablets in the pack they arrive in. Foundayo is sensitive to light, so the original packaging is there to protect it.
Doses and prices
Every price includes your online consultation, your medication, delivery, and ongoing support from our clinical team. There are no hidden fees. Foundayo is subject to clinical approval — if treatment isn't suitable for you, you won't be charged.
Ready to start your weight loss journey with Foundayo?
Getting started is simple and completely online — no GP appointment needed. Our UK Licensed Clinicians will assess your suitability and issue your prescription the same day.
- 1
Complete Your Online Consultation
Fill out our confidential medical questionnaire.
- 2
Clinician Review
Our clinician will review your consultation and verify your suitability for tablet treatment. Your prescription will be issued on the same day.
- 3
Receive Your Tablets
Fast Discreet delivery - Tracked 48-hour delivery via Royal Mail.
Our Clinical Team
Qualified, registered healthcare professionals
Daud Khawaja
Clinical Lead
GPhC: 2222854
Suhail Khan
Clinical Director
GPhC: 2082431
Abrar Rehman
Superintendent Pharmacist
GPhC: 2044890
Real results
Rated Excellent on Trustpilot
“Being able to just take a tablet instead of remembering an injection every week has made this so much easier to stick with.”
Priya, UK
“No fridge, no needles, and it arrived in a plain box the next day. Genuinely straightforward.”
Tom, UK
“The consultation was quick and the clinician actually took time to go through my history. Felt properly looked after.”
Sarah, UK